Salary estimates are based on 1 salaries submitted anonymously to Glassdoor by Neurosurgeon employees in San Francisco, CA. The average salary for a Neurosurgeon is $848,937 in San Francisco, CA. Salary estimates are based on 1 salaries submitted anonymously to Glassdoor by Neurosurgeon employees in San Francisco, CA. This is 25% higher (+$125,399) than the average surgeon neurosurgery salary in the United States. The average pay for a Neurosurgeon is $636,600 a year and $306 an hour in San Francisco, California, United States. The average salary range for a Neurosurgeon is between $382,099 and $1,002,526.On average, a Doctorate Degree is the highest level of education for a Neurosurgeon. In addition, they earn an average bonus of $152,021. The average salary for a Neurosurgeon is $847,876 in San Francisco, CA. The average surgeon neurosurgery salary in San Francisco, California is $636,324 or an equivalent hourly rate of $306. Salaries for Related Job Titles Find the average salary for a Neurosurgeon in San Francisco, CA from Ladders’ database of over 240,000 jobs that pay over 100K. This is 25% higher (+$124,568) than the average medical neurosurgeon salary in the United States. In addition, they earn an average bonus of $153,036. The average medical neurosurgeon salary in San Francisco, California is $632,104 or an equivalent hourly rate of $304. How much does a Neurosurgeon make in San Francisco, CA?