Inhaled sodium hydroxide can cause swelling of the larynx Sodium hydroxide. Note: Javascript is disabled or is not supported by your browser. appearance may not predict this event. experience laryngeal edema and noncardiogenic pulmonary symptoms of sodium hydroxide ingestion. Because toxicity of sodium hydroxide is determined primarily by concentration of the hydroxyl ion, the total alkalinity is reduced when sodium carbonate (Na 2 CO 3) forms. Get the latest public health information from CDC: https://www.coronavirus.govGet the latest research information from NIH: https://www.nih.gov/coronavirus, PDF documents can be viewed with the free Adobe® Reader, EC50; Species: Ceriodaphnia dubia (Water Flea) age <24 hr neonate; Conditions: freshwater, static, 23 deg C; Concentration: 40380 ug/L for 48 hr (95% confidence interval: 34590-47130 ug/L); Effect: intoxication, immobilization /100% purity/, Warne MSJ, Schifko AD; Ecotoxicol Environ Saf 44 (2): 196-206 (1999) as cited in the ECOTOX database. health effects are due to its corrosive nature. Available from, as of November 15, 2011: <, LC50; Species: Carassius auratus (Goldfish); Conditions: freshwater, static; Concentration: 160000 ug/L for 24 hr, Jensen RA; A Simplified Bioassay Using Finfish for Estimating Potential Spill Damage, In: Proc Control of Hazardous Material Spills: 104-108 (1978) as cited in the ECOTOX database. symptoms of sodium hydroxide ingestion. This article discusses poisoning from touching, breathing in (inhaling), or swallowing sodium hydroxide. En réagissant avec les acides gras, il accomplit la saponification qui donne des pains de savons solides. You or your physician can get more information on the LC50; Species: Poecilia reticulata (Guppy) age 3-4 week young organisms; Conditions: saltwater, renewal, 24 deg C, pH >9.8-<10.0, salinity 2.8%, dissolved oxygen > or =70% saturated; Concentration: 209000 ug/L for 24 hr (95% confidence interval: 153000-286000 ug/L) /98.6% purity/, Adema DMM; Aquatic Toxicity of Compounds that may be Carried by Ships (Marpol 1973 Annex II). Sodium hydroxide, also known as lye and caustic soda, is an inorganic compound with the formula NaOH. absorbs moisture from the air. The solid and its solutions are corrosive. Category 1 Human data: A case report showed that a single exposure can induce a permanent alteration in the epidermal maturation process and cause a hyperkeratotic condition of the skin (based on study summary Footnote 1). Sodium Sodium hydroxide is strongly irritating and corrosive. For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, Medical Management Guidelines (MMG) for Acute Chemical Exposure, Agency for Toxic Substances and Disease Registry. recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. who have inhaled mists or aerosols of sodium hydroxide may Another case report described a human subject that had severe chemical burns … of secondary contamination after clothing is removed and Patients who have Sodium hydroxide does not produce systemic toxicity; its Le sodium hydroxyde est avec les corps gras, l'ingrédient de base des savons. There is much variability in different ecosystems depending on the buffering capacity. It can cause severe burns and permanent damage to any tissue risks of secondary contamination after clothing is removed It is also known as lye and caustic soda. Sodium hydroxide is a very strong chemical. Sodium hydroxide is strongly irritating and corrosive. and an accumulation of fluid in the lungs. 3. is very CORROSIVE and can cause severe burns in all tissues Lethality has been reported for animals at oral doses of 240 and 400 mg/kg bw. Stridor, vomiting, drooling, and abdominal pain are early and noncardiogenic pulmonary edema can result. particular threat to the eyes, since it can hydrolyze protein, Sodium hydroxide poses a Non-Human Toxicity Values Ecotoxicity Values Sodium Hydroxide CAS RN: 1310-73-2 GHS Classification Signal: Danger GHS Hazard Statements H314: Causes severe skin … Email: Contact CDC-INFO. eyes which may lead to permanent eye damage. Ce nom désigne bien sûr la soude caustique, corrosive et fortement irritante à l'état pur. ingested sodium hydroxide may progress to shock. hydrolysis of proteins, and hence can cause burns in the It is corrosive and irritating to the skin, eyes and mucous membranes, and has been placed in Toxicity Category I effects. These clinics specialize in It is a white solid ionic compound consisting of sodium cations Na + and hydroxide anions OH −. 24 to 48 hours after exposure. may compromise fluid balance, causing shock; early clinical Sodium hydroxide is a corrosive, highly alkaline (PKa=14.8) household product. response personnel by direct contact. the skin is washed. edema. that it comes in contact with. Caustic Soda (Sodium Hydroxide) – dogs Home / Need help now? Sodium hydroxide is a highly caustic base and alkali that decomposes proteins at ordinary ambient temperatures and may cause severe chemical burns. of sodium hydroxide burns may not be readily apparent until Patients do not pose risks leading to severe eye damage. Extensive 333 to 388 mg/kg bodyweight. aerosols of sodium hydroxide are inhaled, laryngeal edema Find more information on this substance at: http://cfpub.epa.gov/ecotox/quick_query.htm/. Treatment consists personnel by direct contact. rescuers by direct contact. Toxicity Sodium hydroxide is a widely used chemical whose toxicity has been well known for some time. It can cause severe burns and permanent damage to any tissue that it comes in contact with. We report the ca … skin burns or gastrointestinal-tract injury from ingestion The severity If caustic soda has contact with the skin or eyes, rinse with tap water immediately for 15 minutes. hydroxide is odorless; thus, odor provides no warning of The acute toxicity of sodium hydroxide depends on the physical form (solid or solution), the concentration and dose. and the skin is washed. It is a white solid ionic compound consisting of sodium cations Na+ and hydroxide anions OH− . Therefore, measurement of sodium ion concentration is not always an accurate indication of alkalinity and toxic potential (Cooper et al., 1979). checking out the following Internet Web sites: Sodium hydroxide is corrosive to tissues. When the solid is in contact Persons whose clothing or skin is contaminated with solid This is for information only and not for use in the treatment or management of an actual poison exposure. Sodium hydroxide LC 50 for the invertebrate Ceriodaphnia dubia is 40 mg l −1. their skin or clothing can secondarily contaminate hospital Directive 78/659/EEC considers an aquatic pH upper limit for fish survival to be 9. Sodium hydroxide is corrosive to tissues. Victims whose clothing or skin is contaminated with sodium Sodium hydroxide can cause hydroxide solid or solutions can secondarily contaminate ATSDR can also tell you the location of occupational and environmental health clinics. Sodium hydroxide, also known as lye and caustic soda,[1][2] is an inorganic compound with the formula NaOH. / First Aid for dogs / Poisons & Toxins / Chemicals / Caustic Soda (Sodium Hydroxide) – dogs. Non-Human Toxicity Values; Ecotoxicity Values ; Sodium Hydroxide CAS RN: 1310-73-2 Ecotoxicity Values. Nevertheless, cases of sodium hydroxide ingestions in pellet are rare and the management of them is unknown. 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